The Osteoclasts

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Which of the following is false regarding osteoclasts? a) They secrete acid to demineralize/solubilize hydroxyapatite crystals b) They secrete proteolytic enzymes that degrade collagen fibers c) Under normal steady state conditions, their rate of bone erosion is matched by osteoblastic bone building d) Increases in routine bone loading increases osteoclastic activity e) If systemic osteoclastic activity exceeds systemic osteoblastic activity, bones will become less hard and they will be more likely to fracture.

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